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Chemistry 14C Course Web Page > Forums > OWLS Problems > #4
 
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RA
Registered: 09/29/09
Posts: 22

    10/24/09 at 10:42 PM
Reply with quote#1

Hey,

I was wondering how you know that one of the OH groups is axial for galactose? I had assumed they were all equatorial but that would mean it looks exactly like glucose.

Are we taking glucose to be the "standard" and then applying the differences between axial and equatorial accordingly based on the Fischer projections?  Or is the only way to see the proper conformation to build a model?

vquach
Registered: 10/08/09
Posts: 13

    10/25/09 at 02:11 PM
Reply with quote#2

The best way to determine is definitely a model. For these types of chair conformations there are always groups or hydrogens that will be axial and some will be equatorial. Its not possible for a molecule to be all equatorial (that would definitely be most favored if it were possible).

Also whenever you do a ring flip all equatorial will turn into axial
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